--- title: "oh-my-agent vs autogen" type: "comparison" canonical_url: "https://www.graphcanon.com/compare/first-fluke-oh-my-agent-vs-microsoft-autogen" tools: ["first-fluke-oh-my-agent", "microsoft-autogen"] --- # oh-my-agent vs autogen *GraphCanon updated Jul 15, 2026* ## Verdict Pick oh-my-agent when oh-my-agent is primarily TypeScript; autogen is Python; pick autogen when autogen is primarily Python; oh-my-agent is TypeScript. [oh-my-agent](https://firstfluke.com/oh-my-agent/) reports 1.2k GitHub stars, 135 forks, and 0 open issues, last pushed Jul 14, 2026. [autogen](https://microsoft.github.io/autogen/) has 60k stars, 9.0k forks, and 945 open issues, last pushed Apr 15, 2026. Figures are from public GitHub metadata via [oh-my-agent's repository](https://github.com/first-fluke/oh-my-agent) and [autogen's repository](https://github.com/microsoft/autogen). | | [oh-my-agent](/tools/first-fluke-oh-my-agent.md) | [autogen](/tools/microsoft-autogen.md) | | --- | --- | --- | | Tagline | Portable, vendor-agnostic agent harness for project-specific skills, workflows, and agent teams aligned with your codebase, conventions, and engineering standards. | A programming framework for agentic AI | | Stars | 1,164 | 59,658 | | Forks | 135 | 8,983 | | Open issues | 0 | 945 | | Language | TypeScript | Python | | Adopt for | - | AutoGen is a Python-based framework for developing and managing agentic AI systems. It includes the AutoGen Studio for no-code GUI setup, integrating with various models. | | Persona | - | - | | Runtime | - | - | | License | MIT | CC-BY-4.0 | | Categories | AI Agents | AI Agents, LLM Frameworks | ## Trust and health _Sourced signals - not a safety guarantee. No winner column._ | | [oh-my-agent](/tools/first-fluke-oh-my-agent.md) | [autogen](/tools/microsoft-autogen.md) | | --- | --- | --- | | Maintenance | Very active (96%) | Steady (60%) | | Days since push | 0d | 87d | | Open issues (now) | 0 | 945 | | Full report | [trust report](/tools/first-fluke-oh-my-agent/trust.md) | [trust report](/tools/microsoft-autogen/trust.md) | ## Decision facts: autogen - **Requirements:** Min 4 GB RAM; AutoGen requires Python 3.10 or later.; Ensure security when connecting to MCP servers due to the potential for local command execution and sensitive information exposure. - **Adopt for:** AutoGen is a Python-based framework for developing and managing agentic AI systems. It includes the AutoGen Studio for no-code GUI setup, integrating with various models. ## Choose when ### Choose oh-my-agent if… - oh-my-agent is primarily TypeScript; autogen is Python. - License: oh-my-agent is MIT, autogen is CC-BY-4.0. - Tags unique to oh-my-agent: agent-harness, agent-skills, agentic-coding, ai-agents. ### Choose autogen if… - autogen is primarily Python; oh-my-agent is TypeScript. - License: autogen is CC-BY-4.0, oh-my-agent is MIT. - Requirements: Min 4 GB RAM; AutoGen requires Python 3.10 or later.; Ensure security when connecting to MCP servers due to the potential for local command execution and sensitive information exposure.. - Tags unique to autogen: agentic-agi, agents, ai, autogen. - Also covers LLM Frameworks. - You need a framework that supports integration with multiple AI models via OpenAI's chat completion client. ## When NOT to use oh-my-agent - AI Agents: Don't use an agent loop when a deterministic workflow would do; agents add latency, cost, and non-determinism. ## When NOT to use autogen - If you require tools supporting multiple programming languages beyond Python, as AutoGen is strictly a Python-based framework. - When deploying in environments where connecting to external servers (like those used by MCP) could pose security risks or is prohibited. - You need solutions which do not involve additional installations for server components such as `playwright/mcp`, as AutoGen requires this setup for certain functionalities. ## Common questions ### What is the difference between oh-my-agent and autogen? oh-my-agent: Portable, vendor-agnostic agent harness for project-specific skills, workflows, and agent teams aligned with your codebase, conventions, and engineering standards.. autogen: A programming framework for agentic AI. See the comparison table for live GitHub stats and shared categories. ### When should I choose oh-my-agent over autogen? Choose oh-my-agent over autogen when oh-my-agent is primarily TypeScript; autogen is Python; License: oh-my-agent is MIT, autogen is CC-BY-4.0; Tags unique to oh-my-agent: agent-harness, agent-skills, agentic-coding, ai-agents. ### When should I choose autogen over oh-my-agent? Choose autogen over oh-my-agent when autogen is primarily Python; oh-my-agent is TypeScript; License: autogen is CC-BY-4.0, oh-my-agent is MIT; Requirements: Min 4 GB RAM; AutoGen requires Python 3.10 or later.; Ensure security when connecting to MCP servers due to the potential for local command execution and sensitive information exposure.; Tags unique to autogen: agentic-agi, agents, ai, autogen; Also covers LLM Frameworks; You need a framework that supports integration with multiple AI models via OpenAI's chat completion client. ### When should I avoid oh-my-agent? AI Agents: Don't use an agent loop when a deterministic workflow would do; agents add latency, cost, and non-determinism. ### When should I avoid autogen? If you require tools supporting multiple programming languages beyond Python, as AutoGen is strictly a Python-based framework. When deploying in environments where connecting to external servers (like those used by MCP) could pose security risks or is prohibited. You need solutions which do not involve additional installations for server components such as `playwright/mcp`, as AutoGen requires this setup for certain functionalities. ### Is oh-my-agent or autogen more popular on GitHub? autogen has more GitHub stars (59,658 vs 1,164). Stars measure visibility, not whether either tool fits your constraints. ### Are oh-my-agent and autogen open source? Yes - both are open-source projects on GitHub (oh-my-agent: MIT, autogen: CC-BY-4.0). ### Where can I find alternatives to oh-my-agent or autogen? GraphCanon lists graph-backed alternatives at [oh-my-agent alternatives](/tools/first-fluke-oh-my-agent/alternatives) and [autogen alternatives](/tools/microsoft-autogen/alternatives) ([oh-my-agent markdown twin](/tools/first-fluke-oh-my-agent/alternatives.md), [autogen markdown twin](/tools/microsoft-autogen/alternatives.md)), ranked by typed relationship edges rather than popularity votes. ### Is there a machine-readable version of this comparison? Yes. The markdown twin at [this comparison](/compare/first-fluke-oh-my-agent-vs-microsoft-autogen.md) mirrors this page for agents and LLM crawlers, with the same stats table and FAQ answers. ### Which is better maintained, oh-my-agent or autogen? oh-my-agent: Very active. autogen: Steady. Compare maintenance labels, days since push, and release cadence in the trust section below - stars alone do not measure maintenance. ### Where are the full trust reports for oh-my-agent and autogen? GraphCanon publishes per-repo trust reports with dated maintenance, provenance, and scan summaries: [oh-my-agent trust report](/tools/first-fluke-oh-my-agent/trust); [autogen trust report](/tools/microsoft-autogen/trust). --- **Machine-readable endpoints** - JSON: [`/api/graphcanon/graph?tool=first-fluke-oh-my-agent`](/api/graphcanon/graph?tool=first-fluke-oh-my-agent) - LLM index: [/llms.txt](/llms.txt) - Full corpus: [/llms-full.txt](/llms-full.txt) _GraphCanon - The knowledge graph for AI development. https://www.graphcanon.com/_