Comparison
autogen vs sre
Verdict
Pick autogen if autoGen is a Python-based framework for developing and managing agentic AI systems. It includes the AutoGen Studio for no-code GUI setup, integrating with various models; pick sre if smythOS Runtime Environment (SRE) is a TypeScript-based open-source runtime framework designed for developing, managing and running intelligent agents in various environments.
Markdown twin · autogen alternatives · sre alternatives
GraphCanon updated 1d
Trust & integrity
| Signal | autogen | sre |
|---|---|---|
| Maintenance | Slowing (107d since push) As of 3w · github_public_v1 | Slowing (139d since push) As of 1d · github_public_v1 |
| Provenance | Not a fork · Organization account As of 3w · github_public_v1 | Not a fork · Organization account As of 1d · github_public_v1 |
| OSV dependency advisories | No lockfile (source not queried) As of 1mo · osv@v1 | No lockfile (source not queried) As of 1mo · osv@v1 |
| deps.dev advisories | Not queried deps.dev@v1 | Not queried deps.dev@v1 |
| OpenSSF Scorecard | Not queried openssf-scorecard@v1 | Not queried openssf-scorecard@v1 |
Tagline
- autogen
- A programming framework for agentic AI
- sre
- Cloud-native runtime for building, running, and managing intelligent agents
Stars
- autogen
- 60k
- sre
- 1.3k
Forks
- autogen
- 9.1k
- sre
- 201
Open issues
- autogen
- 970
- sre
- 34
Language
- autogen
- Python
- sre
- TypeScript
Adopt for
- autogen
- AutoGen is a Python-based framework for developing and managing agentic AI systems. It includes the AutoGen Studio for no-code GUI setup, integrating with various models.
- sre
- SmythOS Runtime Environment (SRE) is a TypeScript-based open-source runtime framework designed for developing, managing and running intelligent agents in various environments.
Persona
- autogen
- -
- sre
- -
Runtime
- autogen
- -
- sre
- -
License
- autogen
- CC-BY-4.0
- sre
- MIT
Last pushed
- autogen
- Apr 15, 2026
- sre
- Apr 3, 2026
Categories
- autogen
- AI Agents, LLM Frameworks
- sre
- AI Agents
Trust and health
Days since push
- autogen
- 107d
- sre
- 139d
Open issues (now)
- autogen
- 970
- sre
- 34
Stars delta
- autogen
- Unknown
- sre
- +6 (30d)
Open issues delta
- autogen
- Unknown
- sre
- +1 (30d)
Full report
- autogen
- Trust report
- sre
- Trust report
Typed relationship
autogen successor sreAutogen is a programming framework designed for developing autonomous AI agents that can work independently or collaboratively with humans, whereas SmythOS Runtime Environment (SRE) provides a more advanced set of OS-level abstractions and cloud-native capabilities specifically aimed at managing and scaling production AI agents. The successor relationship indicates SRE builds upon the foundational
Shared compatibility
- Node.js · autogen: Node.js runtime · sre: Node.js runtime
Choose autogen if…
- autogen is primarily Python; sre is TypeScript.
- License: autogen is CC-BY-4.0, sre is MIT.
- Requirements: Min 4 GB RAM; AutoGen requires Python 3.10 or later.; Ensure security when connecting to MCP servers due to the potential for local command execution and sensitive information exposure..
- Autogen is a programming framework designed for developing autonomous AI agents that can work independently or collaboratively with humans, whereas SmythOS Runtime Environment (SRE) provides a more advanced set of OS-level abstractions and cloud-native capabilities specifically aimed at managing and scaling production AI agents. The successor relationship indicates SRE builds upon the foundational
- Tags unique to autogen: agentic-agi, agents, ai, autogen.
- Also covers LLM Frameworks.
- You need a framework that supports integration with multiple AI models via OpenAI's chat completion client.
When NOT to use autogen
- If you require tools supporting multiple programming languages beyond Python, as AutoGen is strictly a Python-based framework.
- When deploying in environments where connecting to external servers (like those used by MCP) could pose security risks or is prohibited.
- You need solutions which do not involve additional installations for server components such as `playwright/mcp`, as AutoGen requires this setup for certain functionalities.
Choose sre if…
- sre is primarily TypeScript; autogen is Python.
- License: sre is MIT, autogen is CC-BY-4.0.
- Autogen is a programming framework designed for developing autonomous AI agents that can work independently or collaboratively with humans, whereas SmythOS Runtime Environment (SRE) provides a more advanced set of OS-level abstractions and cloud-native capabilities specifically aimed at managing and scaling production AI agents. The successor relationship indicates SRE builds upon the foundational
- Tags unique to sre: agent-framework, agi, autonomous-agents, multi-agent-systems.
- Use SRE if you are working with agentic AI projects that need to be deployed across multiple environments such as local, cloud, or edge locations.
When NOT to use sre
- Avoid SRE if the project requirements are focused on languages other than TypeScript as it is specifically built with TypeScript in mind.
- If your use case prioritizes immediate access to a mature and widely supported SDK over an open-source framework, another tool might offer more comprehensive support out of the box.
Explore
Sources
Every stat on this page traces to a dated GitHub sync, license file, enrichment field, or trust scan.
- GitHub stars (microsoft/autogen) · observed Aug 1, 2026
- GitHub forks (microsoft/autogen) · observed Aug 1, 2026
- Last push (microsoft/autogen) · observed Apr 15, 2026
- License file (CC-BY-4.0) · observed Aug 1, 2026
- Decision facts (enrichment) · observed Jul 11, 2026
- Trust scan (lockfile / OSV) · observed Jul 11, 2026
- GitHub stars (SmythOS/sre) · observed Aug 20, 2026
- GitHub forks (SmythOS/sre) · observed Aug 20, 2026
- Last push (SmythOS/sre) · observed Apr 3, 2026
- License file (MIT) · observed Aug 20, 2026
- Decision facts (enrichment) · observed Jul 12, 2026
- Trust scan (lockfile / OSV) · observed Jul 11, 2026
GitHub stars on cards: autogen 60k · sre 1.3k (synced Aug 1, 2026).
Common questions
- What is the difference between autogen and sre?
- autogen: A programming framework for agentic AI. sre: Cloud-native runtime for building, running, and managing intelligent agents. See the comparison table for live GitHub stats and shared categories.
- When should I choose autogen over sre?
- Choose autogen over sre when autogen is primarily Python; sre is TypeScript; License: autogen is CC-BY-4.0, sre is MIT; Requirements: Min 4 GB RAM; AutoGen requires Python 3.10 or later.; Ensure security when connecting to MCP servers due to the potential for local command execution and sensitive information exposure.; Autogen is a programming framework designed for developing autonomous AI agents that can work independently or collaboratively with humans, whereas SmythOS Runtime Environment (SRE) provides a more advanced set of OS-level abstractions and cloud-native capabilities specifically aimed at managing and scaling production AI agents. The successor relationship indicates SRE builds upon the foundational; Tags unique to autogen: agentic-agi, agents, ai, autogen; Also covers LLM Frameworks; You need a framework that supports integration with multiple AI models via OpenAI's chat completion client.
- When should I choose sre over autogen?
- Choose sre over autogen when sre is primarily TypeScript; autogen is Python; License: sre is MIT, autogen is CC-BY-4.0; Autogen is a programming framework designed for developing autonomous AI agents that can work independently or collaboratively with humans, whereas SmythOS Runtime Environment (SRE) provides a more advanced set of OS-level abstractions and cloud-native capabilities specifically aimed at managing and scaling production AI agents. The successor relationship indicates SRE builds upon the foundational; Tags unique to sre: agent-framework, agi, autonomous-agents, multi-agent-systems; Use SRE if you are working with agentic AI projects that need to be deployed across multiple environments such as local, cloud, or edge locations.
- When should I avoid autogen?
- If you require tools supporting multiple programming languages beyond Python, as AutoGen is strictly a Python-based framework. When deploying in environments where connecting to external servers (like those used by MCP) could pose security risks or is prohibited. You need solutions which do not involve additional installations for server components such as
playwright/mcp, as AutoGen requires this setup for certain functionalities. - When should I avoid sre?
- Avoid SRE if the project requirements are focused on languages other than TypeScript as it is specifically built with TypeScript in mind. If your use case prioritizes immediate access to a mature and widely supported SDK over an open-source framework, another tool might offer more comprehensive support out of the box.
- Is autogen or sre more popular on GitHub?
- autogen has more GitHub stars (60,139 vs 1,291). Stars measure visibility, not whether either tool fits your constraints.
- Are autogen and sre open source?
- Yes - both are open-source projects on GitHub (autogen: CC-BY-4.0, sre: MIT).
- Where can I find alternatives to autogen or sre?
- GraphCanon lists graph-backed alternatives at autogen alternatives and sre alternatives (autogen markdown twin, sre markdown twin), ranked by typed relationship edges rather than popularity votes.
- Is there a machine-readable version of this comparison?
- Yes. The markdown twin at this comparison mirrors this page for agents and LLM crawlers, with the same stats table and FAQ answers.
- Which is better maintained, autogen or sre?
- autogen: Slowing. sre: Slowing. Compare maintenance labels, days since push, and release cadence in the trust section below - stars alone do not measure maintenance.
- Where are the full trust reports for autogen and sre?
- GraphCanon publishes per-repo trust reports with dated maintenance, provenance, and scan summaries: autogen trust report; sre trust report.