Comparison
autogen vs sre
Verdict
Pick autogen if autoGen is a Python-based framework for developing agentic AI systems, offering tools for integrating with external models and services, and a no-code GUI for easier interaction; pick sre if smythOS Runtime Environment (SRE) is a TypeScript-based open-source runtime framework designed for developing, managing and running intelligent agents in various environments.
Markdown twin · autogen alternatives · sre alternatives
GraphCanon updated Sep 20, 2026
16views this month
Trust & integrity
| Signal | autogen | sre |
|---|---|---|
| Maintenance | Slowing (155d since push) As of Sep 18, 2026 · github_public_v1 | Slowing (170d since push) As of Sep 20, 2026 · github_public_v1 |
| Provenance | Not a fork · Organization account As of Sep 18, 2026 · github_public_v1 | Not a fork · Organization account As of Sep 20, 2026 · github_public_v1 |
| OSV dependency advisories | No lockfile (source not queried) As of Sep 18, 2026 · osv@v1 | No lockfile (source not queried) As of Jul 11, 2026 · osv@v1 |
| deps.dev advisories | Not queried deps.dev@v1 | Not queried deps.dev@v1 |
| OpenSSF Scorecard | Not queried openssf-scorecard@v1 | Not queried openssf-scorecard@v1 |
Tagline
- autogen
- A programming framework for agentic AI
- sre
- Cloud-native runtime for building, running, and managing intelligent agents
Stars
- autogen
- 61k
- sre
- 1.3k
Forks
- autogen
- 9.2k
- sre
- 202
Open issues
- autogen
- 1.1k
- sre
- 35
Language
- autogen
- Python
- sre
- TypeScript
Adopt for
- autogen
- AutoGen is a Python-based framework for developing agentic AI systems, offering tools for integrating with external models and services, and a no-code GUI for easier interaction.
- sre
- SmythOS Runtime Environment (SRE) is a TypeScript-based open-source runtime framework designed for developing, managing and running intelligent agents in various environments.
Persona
- autogen
- -
- sre
- -
Runtime
- autogen
- -
- sre
- -
License
- autogen
- CC-BY-4.0
- sre
- MIT
Last pushed
- autogen
- Apr 15, 2026
- sre
- Apr 3, 2026
Categories
- autogen
- AI Agents, LLM Frameworks
- sre
- AI Agents
Trust and health
Days since push
- autogen
- 155d
- sre
- 170d
Open issues (now)
- autogen
- 1.1k
- sre
- 35
Stars delta
- autogen
- +897 (30d)
- sre
- +2 (30d)
Open issues delta
- autogen
- +105 (30d)
- sre
- +1 (30d)
Full report
- autogen
- Trust report
- sre
- Trust report
Typed relationship
autogen successor sreAutogen is a programming framework designed for developing autonomous AI agents that can work independently or collaboratively with humans, whereas SmythOS Runtime Environment (SRE) provides a more advanced set of OS-level abstractions and cloud-native capabilities specifically aimed at managing and scaling production AI agents. The successor relationship indicates SRE builds upon the foundational
Shared compatibility
- Node.js · autogen: Node.js runtime · sre: Node.js runtime
Choose autogen if…
- autogen is primarily Python; sre is TypeScript.
- License: autogen is CC-BY-4.0, sre is MIT.
- Requirements: AutoGen requires Python 3.10 or later.; Installation of AutoGen Studio is optional for no-code GUI interaction.; Ensure trusted MCP servers are used to avoid security risks..
- Autogen is a programming framework designed for developing autonomous AI agents that can work independently or collaboratively with humans, whereas SmythOS Runtime Environment (SRE) provides a more advanced set of OS-level abstractions and cloud-native capabilities specifically aimed at managing and scaling production AI agents. The successor relationship indicates SRE builds upon the foundational
- Tags unique to autogen: agentic, agentic-agi, agents, ai.
- Also covers LLM Frameworks.
- When you need a structured approach to create and manage AI agents with Python.
When NOT to use autogen
- If your project requires a version of Python earlier than 3.10, as AutoGen is not compatible.
- When you need a framework that does not rely on potentially untrusted MCP servers for execution.
- If your project does not require or benefit from the no-code GUI provided by AutoGen Studio.
- When you prefer a framework that does not involve the complexity of setting up and managing multiple MCP servers.
Choose sre if…
- sre is primarily TypeScript; autogen is Python.
- License: sre is MIT, autogen is CC-BY-4.0.
- Autogen is a programming framework designed for developing autonomous AI agents that can work independently or collaboratively with humans, whereas SmythOS Runtime Environment (SRE) provides a more advanced set of OS-level abstractions and cloud-native capabilities specifically aimed at managing and scaling production AI agents. The successor relationship indicates SRE builds upon the foundational
- Tags unique to sre: agent-framework, agi, autonomous-agents, multi-agent-systems.
- Use SRE if you are working with agentic AI projects that need to be deployed across multiple environments such as local, cloud, or edge locations.
When NOT to use sre
- Avoid SRE if the project requirements are focused on languages other than TypeScript as it is specifically built with TypeScript in mind.
- If your use case prioritizes immediate access to a mature and widely supported SDK over an open-source framework, another tool might offer more comprehensive support out of the box.
Explore
Sources
Every stat on this page traces to a dated GitHub sync, license file, enrichment field, or trust scan.
- GitHub stars (microsoft/autogen) · observed Sep 20, 2026
- GitHub forks (microsoft/autogen) · observed Sep 20, 2026
- Last push (microsoft/autogen) · observed Apr 15, 2026
- License file (CC-BY-4.0) · observed Sep 20, 2026
- Decision facts (enrichment) · observed Sep 18, 2026
- Trust scan (lockfile / OSV) · observed Sep 18, 2026
- GitHub stars (SmythOS/sre) · observed Sep 20, 2026
- GitHub forks (SmythOS/sre) · observed Sep 20, 2026
- Last push (SmythOS/sre) · observed Apr 3, 2026
- License file (MIT) · observed Sep 20, 2026
- Decision facts (enrichment) · observed Jul 12, 2026
- Trust scan (lockfile / OSV) · observed Jul 11, 2026
GitHub stars on cards: autogen 61k · sre 1.3k (synced Sep 20, 2026).
Common questions
- What is the difference between autogen and sre?
- autogen: A programming framework for agentic AI. sre: Cloud-native runtime for building, running, and managing intelligent agents. See the comparison table for live GitHub stats and shared categories.
- When should I choose autogen over sre?
- Choose autogen over sre when autogen is primarily Python; sre is TypeScript; License: autogen is CC-BY-4.0, sre is MIT; Requirements: AutoGen requires Python 3.10 or later.; Installation of AutoGen Studio is optional for no-code GUI interaction.; Ensure trusted MCP servers are used to avoid security risks.; Autogen is a programming framework designed for developing autonomous AI agents that can work independently or collaboratively with humans, whereas SmythOS Runtime Environment (SRE) provides a more advanced set of OS-level abstractions and cloud-native capabilities specifically aimed at managing and scaling production AI agents. The successor relationship indicates SRE builds upon the foundational; Tags unique to autogen: agentic, agentic-agi, agents, ai; Also covers LLM Frameworks; When you need a structured approach to create and manage AI agents with Python.
- When should I choose sre over autogen?
- Choose sre over autogen when sre is primarily TypeScript; autogen is Python; License: sre is MIT, autogen is CC-BY-4.0; Autogen is a programming framework designed for developing autonomous AI agents that can work independently or collaboratively with humans, whereas SmythOS Runtime Environment (SRE) provides a more advanced set of OS-level abstractions and cloud-native capabilities specifically aimed at managing and scaling production AI agents. The successor relationship indicates SRE builds upon the foundational; Tags unique to sre: agent-framework, agi, autonomous-agents, multi-agent-systems; Use SRE if you are working with agentic AI projects that need to be deployed across multiple environments such as local, cloud, or edge locations.
- When should I avoid autogen?
- If your project requires a version of Python earlier than 3.10, as AutoGen is not compatible. When you need a framework that does not rely on potentially untrusted MCP servers for execution. If your project does not require or benefit from the no-code GUI provided by AutoGen Studio. When you prefer a framework that does not involve the complexity of setting up and managing multiple MCP servers.
- When should I avoid sre?
- Avoid SRE if the project requirements are focused on languages other than TypeScript as it is specifically built with TypeScript in mind. If your use case prioritizes immediate access to a mature and widely supported SDK over an open-source framework, another tool might offer more comprehensive support out of the box.
- Is autogen or sre more popular on GitHub?
- autogen has more GitHub stars (61,036 vs 1,293). Stars measure visibility, not whether either tool fits your constraints.
- Are autogen and sre open source?
- Yes - both are open-source projects on GitHub (autogen: CC-BY-4.0, sre: MIT).
- Where can I find alternatives to autogen or sre?
- GraphCanon lists graph-backed alternatives at autogen alternatives and sre alternatives (autogen markdown twin, sre markdown twin), ranked by typed relationship edges rather than popularity votes.
- Is there a machine-readable version of this comparison?
- Yes. The markdown twin at this comparison mirrors this page for agents and LLM crawlers, with the same stats table and FAQ answers.
- Which is better maintained, autogen or sre?
- autogen: Slowing. sre: Slowing. Compare maintenance labels, days since push, and release cadence in the trust section below - stars alone do not measure maintenance.
- Where are the full trust reports for autogen and sre?
- GraphCanon publishes per-repo trust reports with dated maintenance, provenance, and scan summaries: autogen trust report; sre trust report.